Blar i forfatter "Lauksund, Reidunn Silje"

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    • Induction of Atlantic salmon type I interferon and antagonism by infectious pancreatic necrosis virus 

      Lauksund, Reidunn Silje (Doctoral thesis; Doktorgradsavhandling, 2014-04-08)
      Viral infections are a leading cause of mortality in the farming of Atlantic salmon in Norway. Viral outbreaks cause heavy losses each year, and one of the most predominant viral diseases is infectious pancreatic necrosis (IPN). The virus causing this disease, the infectious pancreatic necrosis virus (IPNV), belongs to the Birnaviridae family of viruses with a double-stranded RNA (dsRNA) genome. ...

    • Infectious pancreatic necrosis virus proteins VP2, VP3, VP4 and VP5 antagonize IFNa1 promoter activation while VP1 induces IFNa1 

      Lauksund, Reidunn Silje; Greiner-Tollersrud, Linn; Chang, Chia Jung; Robertsen, Børre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Infectious pancreatic necrosis virus (IPNV) is one of the major viral pathogens causing disease in farmed Atlantic salmon worldwide. In the present work we show that several of the IPN proteins have powerful antagonistic properties against type I IFN induction in Atlantic salmon. Each of the five IPNV genes cloned into an expression vector were tested for the ability to influence activation of the ...

    • Sequence Analysis of the Genome of Piscine Orthoreovirus (PRV) Associated with Heart and Skeletal Muscle Inflammation (HSMI) in Atlantic Salmon (Salmo salar) 

      Markussen, Turhan; Dahle, Maria Krudtaa; Tengs, Torstein; Løvoll, Marie Therese; Finstad, Øystein Wessel; Wiik-Nielsen, Christer R.; Grove, Søren; Lauksund, Reidunn Silje; Robertsen, Børre; Rimstad, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Piscine orthoreovirus (PRV) is associated with heart- and skeletal muscle inflammation (HSMI) of farmed Atlantic salmon (Salmo salar). We have performed detailed sequence analysis of the PRV genome with focus on putative encoded proteins, compared with prototype strains from mammalian (MRV T3D)- and avian orthoreoviruses (ARV-138), and aquareovirus (GCRV-873). Amino acid identities were low for ...

    • Sequence Analysis of the Genome of Piscine Orthoreovirus (PRV) Associated with Heart and Skeletal Muscle Inflammation (HSMI) in Atlantic Salmon (Salmo salar) 

      Markussen, Turhan; Dahle, Maria Krudtaa; Tengs, Torstein; Løvoll, Marie Therese; Finstad, Øystein Wessel; Wiik-Nielsen, Christer R.; Grove, Søren; Lauksund, Reidunn Silje; Robertsen, Børre; Rimstad, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Piscine orthoreovirus (PRV) is associated with heart- and skeletal muscle inflammation (HSMI) of farmed Atlantic salmon (Salmo salar). We have performed detailed sequence analysis of the PRV genome with focus on putative encoded proteins, compared with prototype strains from mammalian (MRV T3D)- and avian orthoreoviruses (ARV-138), and aquareovirus (GCRV-873). Amino acid identities were low for ...